tasquinimod

Base Information

Chemical Name:tasquinimod
CAS No.:254964-60-8
Molecular Formula:C20H17 F3 N2 O4
Molecular Weight:406.361
Hs Code.:
Mol file:254964-60-8.mol

Synonyms:N-Methyl-N-(4-trifluoromethylphenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxoquinoline-3-carboxamide;Tasquinimod

Suppliers and Price of tasquinimod

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Tasquinimod
100mg
$ 1655.00

TRC
Tasquinimod
25mg
$ 550.00

Tocris
Tasquinimod ≥98%(HPLC)
25
$ 295.00

Medical Isotopes, Inc.
Tasquinimod
5 mg
$ 675.00

Medical Isotopes, Inc.
Tasquinimod
25 mg
$ 1025.00

Medical Isotopes, Inc.
Tasquinimod
100 mg
$ 2575.00

Matrix Scientific
4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-carboxamide 97%
1g
$ 2700.00

Matrix Scientific
4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-carboxamide 97%
250mg
$ 1764.00

DC Chemicals
Tasquinimod(ABR-215050) >98%
250 mg
$ 900.00

Crysdot
Tasquinimod 98+%
25mg
$ 455.00

Total 41 raw suppliers

Chemical Property of tasquinimod

Chemical Property:

Boiling Point:501.5±50.0 °C(Predicted)
PKA:4.50±1.00(Predicted)
PSA：71.77000
Density:1.427±0.06 g/cm3(Predicted)
LogP:3.54810
Storage Temp.:2-8°C
Solubility.:insoluble in H2O; ≥20.32 mg/mL in DMSO; ≥4.75 mg/mL in EtOH with gentle warming and ultrasonic

Purity/Quality:

99%, ^*data from raw suppliers

Tasquinimod ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Tasquinimod is an orally-active quinoline-3-carboxamide derived from roquinimex, an immunomodulatory quinolone with applications in some cancers and autoimmune diseases. Tasquinimod inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer. While its precise mechanism of action remains unclear, tasquinimod has been reported to alter signaling through S100A9, thrombospondin-1, HIF-1α, androgen receptor, VEGF, and HDAC3/4.
Uses Tasquinimod is an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making tasquinimod and anti-cancer agent.

Technology Process of tasquinimod

There total 9 articles about tasquinimod which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%