3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-

Base Information

Chemical Name:3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-
CAS No.:248282-18-0
Molecular Formula:C12H11NO5
Molecular Weight:249.223
Hs Code.:

Synonyms:3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-

Suppliers and Price of 3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 10 raw suppliers

Chemical Property of 3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-

Chemical Property:

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo-

There total 7 articles about 3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-5-Methoxy-1-Methyl-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 248282-13-5
1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxylic acid ethyl ester

: 248282-18-0
1,2-Dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxylic acid

Guidance literature:: With hydrogenchloride; acetic anhydride;

Reference yield:

: 91105-97-4
5-methoxy-1-methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

: 248282-18-0
1,2-Dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 5 h / 85 °C

2: HCl / acetic acid / 6 h / 60 °C

With hydrogenchloride; sodium hydride; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm031044w

Reference yield:

: 53600-33-2
6-methoxyanthranilic acid

: 248282-18-0
1,2-Dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: dioxane / 1 h / 20 °C

2: NaH / dimethylformamide / 5 h / 20 °C

3: NaH / dimethylformamide / 5 h / 85 °C

4: HCl / acetic acid / 6 h / 60 °C

With hydrogenchloride; sodium hydride; In 1,4-dioxane; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm031044w