methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside

Base Information

• Chemical Name: methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside
• CAS No.: 657395-21-6
• Molecular Formula: C₇₂H₇₀N₆O₁₇
• Molecular Weight: 1291.38
• Mol file: 657395-21-6.mol

Synonyms:methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside

Chemical Property of methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside

There total 1 articles about methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-6-O-levulinyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside (657395-08-9) → methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside (657395-21-6)

Guidance literature:

With acetic acid; hydrazine; In ethanol; toluene; at 20 ℃; for 2h;

DOI:10.1021/ja038244h

Reference yield:

methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside (657395-21-6) → methyl [2-azido-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(3-O-benzyl-α-L-idopyranosyluronicacid)-(1->4)-2-azido-3-O-benzyl-2-deoxy-α-D-glucopyranoside (657395-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: TEMPO; aq. NaOCl

2: NaOMe

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium methylate;

DOI:10.1002/jccs.200400175

Reference yield:

methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside (657395-21-6) → 6-(5-azido-4-benzyloxy-6-methoxy-2-sulfooxymethyl-tetrahydro-pyran-3-yloxy)-3-[3-azido-4-benzyloxy-5-(naphthalen-2-ylmethoxy)-6-sulfooxymethyl-tetrahydro-pyran-2-yloxy]-4-benzyloxy-5-sulfooxy-tetrahydro-pyran-2-carboxylic acid (657395-23-8)

Guidance literature:

Multi-step reaction with 3 steps

1: TEMPO; aq. NaOCl

2: NaOMe

3: SO₃; Et₃N

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sulfur trioxide; sodium methylate; triethylamine;

DOI:10.1002/jccs.200400175

upstream raw materials:

methyl [2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(2-O-benzoyl-3-O-benzyl-6-O-levulinyl-α-L-idopyranosyl)-(1->4)-2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside

Downstream raw materials:

methyl [2-azido-3-O-benzyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-(1->4)-(3-O-benzyl-α-L-idopyranosyluronicacid)-(1->4)-2-azido-3-O-benzyl-2-deoxy-α-D-glucopyranoside

6-(5-azido-4-benzyloxy-6-methoxy-2-sulfooxymethyl-tetrahydro-pyran-3-yloxy)-3-[3-azido-4-benzyloxy-5-(naphthalen-2-ylmethoxy)-6-sulfooxymethyl-tetrahydro-pyran-2-yloxy]-4-benzyloxy-5-sulfooxy-tetrahydro-pyran-2-carboxylic acid