methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Base Information

Chemical Name:methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate
CAS No.:131925-04-7
Molecular Formula:C₂₂H₂₁N₃O₃
Molecular Weight:375.427
Hs Code.:

Synonyms:methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Suppliers and Price of methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

There total 4 articles about methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 131925-03-6
Methyl 5-methyl-10,11-dihydro-5H-pyrrolo<1,2-b><1,2,5>benzotriazepine-11-acetate

: 98-88-4
benzoyl chloride

: 131925-04-7
methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 72h; Heating / reflux;

Reference yield:

: 87948-04-7
N-methyl-N-(2-aminophenyl)-1H-pyrrol-1-ylamine

: 131925-04-7
methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / tetrahydrofuran / 15 h / Ambient temperature

2: 74 percent / POCl₃ / CH₂Cl₂ / 20 h / Heating

3: 90 percent / NaBH₃CN, HCl / ethanol; tetrahydrofuran / 20 h / Ambient temperature

4: 69 percent / Et₃N / tetrahydrofuran / 72 h / Heating

With hydrogenchloride; sodium cyanoborohydride; triethylamine; trichlorophosphate; In tetrahydrofuran; ethanol; dichloromethane;

Reference yield:

: 131925-12-7
5-Methyl-11-methoxycarbonylmethylene-5H,10H-pyrrolo<1,2-b><1,2,5>benzotriazepine

: 131925-04-7
methyl 10,11-dihydro-5-methyl-10-benzoyl-5H-pyrrolo[1,2-b][1,2,5]benzotriazepine-11-acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaBH₃CN, HCl / ethanol; tetrahydrofuran / 20 h / Ambient temperature

2: 69 percent / Et₃N / tetrahydrofuran / 72 h / Heating

With hydrogenchloride; sodium cyanoborohydride; triethylamine; In tetrahydrofuran; ethanol;