1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Base Information

Chemical Name:1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone
CAS No.:1370531-43-3
Molecular Formula:C₂₄H₂₉N₃O₂S₃
Molecular Weight:487.711
Hs Code.:

Synonyms:1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Suppliers and Price of 1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

There total 15 articles about 1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1370531-40-0
(2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolyl[4-(6-methoxy-1,3-benzothiazol-2-yl)-2-nitrophenyl]methanone

: 1370531-43-3
1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Guidance literature:: With tin(II) chloride dihdyrate; In methanol; for 1h; Reflux;
DOI:10.1016/j.ejmech.2012.01.014

Reference yield:

: 96-98-0
4-methyl-3-nitrobenzoic acid

: 1370531-43-3
1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Guidance literature:: Multi-step reaction with 8 steps

1: thionyl chloride; N,N-dimethyl-formamide / benzene / 80 °C

2: triethylamine / tetrahydrofuran / 0 - 20 °C

3: Lawessons reagent / toluene / 60 °C / Reflux

4: Dess-Martin periodane / dichloromethane / 20 °C

5: pyridine; tetra-n-butylammonium permanganate / 12 h / 20 °C

6: thionyl chloride; N,N-dimethyl-formamide / benzene / Reflux

7: triethylamine / tetrahydrofuran / 1.5 h / 0 - 20 °C

8: tin(II) chloride dihdyrate / methanol / 1 h / Reflux

With Lawessons reagent; pyridine; thionyl chloride; tetra-n-butylammonium permanganate; tin(II) chloride dihdyrate; Dess-Martin periodane; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane; toluene; benzene;
DOI:10.1016/j.ejmech.2012.01.014

Reference yield:

: 1370531-36-4
4-(6-methoxy-1,3-benzothiazol-2-yl)-2-nitrobenzoic acid

: 1370531-43-3
1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride; N,N-dimethyl-formamide / benzene / Reflux

2: triethylamine / tetrahydrofuran / 1.5 h / 0 - 20 °C

3: tin(II) chloride dihdyrate / methanol / 1 h / Reflux

With thionyl chloride; tin(II) chloride dihdyrate; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; benzene;
DOI:10.1016/j.ejmech.2012.01.014