(+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile

Base Information

• Chemical Name: (+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile
• CAS No.: 1534343-82-2
• Molecular Formula: C₁₆H₁₆N₂O₂
• Molecular Weight: 268.315
• Mol file: 1534343-82-2.mol

Synonyms:(+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile

Chemical Property of (+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile

Chemical Property:

Purity/Quality:

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Technology Process of (+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile

There total 1 articles about (+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimethylsilyl cyanide (7677-24-9) + C15H15NO2 (1534343-76-4) → (+)-2-benzyloxymethyl-4-oxo-4-(1H-pyrrol-1-yl)butanenitrile (1534343-82-2)

Guidance literature:

trimethylsilyl cyanide; With methanol; C₆₀H₄₈N₂O₄P₂Ru; lithium methanolate; at 0 ℃; for 0.25h; Schlenk technique; Inert atmosphere;

C₁₅H₁₅NO₂; In methanol; tert-butyl methyl ether; at -20 ℃; for 24h; enantioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/ol403545b

upstream raw materials:

trimethylsilyl cyanide

C₁₅H₁₅NO₂