C₂₂H₃₀Br₂O₄

Base Information

• Chemical Name: C₂₂H₃₀Br₂O₄
• CAS No.: 1381781-05-0
• Molecular Formula: C₂₂H₃₀Br₂O₄
• Molecular Weight: 518.286
• Mol file: 1381781-05-0.mol

Synonyms:C₂₂H₃₀Br₂O₄

Chemical Property of C₂₂H₃₀Br₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₃₀Br₂O₄

There total 3 articles about C₂₂H₃₀Br₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-(3,7-dimethyl-octa-2,6-dienyl)-3,5-bis-methoxymethoxy-benzaldehyde (495412-19-6) + carbon tetrabromide (558-13-4) → C22H30Br2O4 (1381781-05-0)

Guidance literature:

With triphenylphosphine; zinc; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1016/j.bmcl.2012.04.062

Reference yield:

methyl 3,5-bis(methoxymethoxy)benzoate (76280-59-6) → C22H30Br2O4 (1381781-05-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C

2.1: 1H-imidazole; dmap / 5 h / 20 °C

3.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C

3.2: 6 h / 20 °C

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

5.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Molecular sieve

6.1: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C

With 1H-imidazole; dmap; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; triphenylphosphine; pyridinium chlorochromate; zinc; In tetrahydrofuran; dichloromethane; 6.1: Ramirez olefination reaction;

DOI:10.1016/j.bmcl.2012.04.062

Reference yield:

4-((2E)-3,7-dimethyl-2,6-octadienyl)-3,5-bis(methoxymethoxy)benzyl alcohol (252679-37-1) → C22H30Br2O4 (1381781-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Molecular sieve

2: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C

With triphenylphosphine; pyridinium chlorochromate; zinc; In dichloromethane; 2: Ramirez olefination reaction;

DOI:10.1016/j.bmcl.2012.04.062

upstream raw materials:

4-(3,7-dimethyl-octa-2,6-dienyl)-3,5-bis-methoxymethoxy-benzaldehyde

carbon tetrabromide

methyl 3,5-bis(methoxymethoxy)benzoate

4-((2E)-3,7-dimethyl-2,6-octadienyl)-3,5-bis(methoxymethoxy)benzyl alcohol

Downstream raw materials:

C₂₅H₃₀O₃

C₂₅H₂₇F₃O₂

C₂₅H₂₇F₃O₂

C₂₄H₂₇FO₂