(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Base Information

Chemical Name:(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone
CAS No.:218451-28-6
Molecular Formula:C₂₅H₂₄Cl₂F₂N₄O₃
Molecular Weight:537.393
Hs Code.:

Synonyms:(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Suppliers and Price of (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

There total 13 articles about (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 216311-22-7
1-(3-aminopropyl)-4-(2,4-dichlorophenyl)-piperidine-4-carbonitrile

: 218449-37-7
4-(3,4-difluorophenyl)-2-oxo-oxazolidine-3-carboxylic acid-4-nitro-phenyl ester

: 218451-28-6
(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; dichloromethane;

Reference yield:

: 34036-07-2
3,4 difluorobenzaldehyde

: 218451-28-6
(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Guidance literature:: Multi-step reaction with 6 steps

1: methanol; trimethylsilyl cyanide

2: sodium hydroxide; LiAlH₄ / water

3: chloroform; ethyl acetate

4: NaH / tetrahydrofuran; water

5: NaH / tetrahydrofuran; hexane

6: hydrogenchloride / tetrahydrofuran; dichloromethane

With hydrogenchloride; sodium hydroxide; LiAlH₄; NaH; In tetrahydrofuran; methanol; hexane; dichloromethane; chloroform; trimethylsilyl cyanide; water; ethyl acetate;

Reference yield:

: 277295-93-9,218449-32-2,1269935-50-3
2-amino-2-(3,4-difluorophenyl)-ethanol

: 218451-28-6
(+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone

Guidance literature:: Multi-step reaction with 4 steps

1: chloroform; ethyl acetate

2: NaH / tetrahydrofuran; water

3: NaH / tetrahydrofuran; hexane

4: hydrogenchloride / tetrahydrofuran; dichloromethane

With hydrogenchloride; NaH; In tetrahydrofuran; hexane; dichloromethane; chloroform; water; ethyl acetate;