2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime

Base Information

• Chemical Name: 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime
• CAS No.: 144946-83-8
• Molecular Formula: C₆₁H₆₅NO₁₁
• Molecular Weight: 988.187
• Mol file: 144946-83-8.mol

Synonyms:2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime

Chemical Property of 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime

There total 3 articles about 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3,6-tri-O-benzyl-4-O-(2′,3′,4′,6′-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucopyranoside (108811-21-8,108811-27-4,115988-74-4,132683-15-9,148968-90-5) → 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime (144946-83-8)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; for 3h; Heating;

Reference yield:

benzyl bromide (100-39-0) → 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime (144946-83-8)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH / dimethylformamide

2: 65 percent / aq. silver nitrate / acetone / 144 h / Ambient temperature

3: 100 percent / 1.) NH₂OH*HCl, AcONa / ethanol / 3 h / Heating

With hydroxylamine hydrochloride; sodium acetate; sodium hydride; silver nitrate; In ethanol; N,N-dimethyl-formamide; acetone;

Reference yield:

2,2',3,3',4',6,6'-hepta-O-benzyl-1β-(p-chlorophenylthio)maltose (144946-76-9) → 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucose oxime (144946-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / aq. silver nitrate / acetone / 144 h / Ambient temperature

2: 100 percent / 1.) NH₂OH*HCl, AcONa / ethanol / 3 h / Heating

With hydroxylamine hydrochloride; sodium acetate; silver nitrate; In ethanol; acetone;

upstream raw materials:

2,3,6-tri-O-benzyl-4-O-(2′,3′,4′,6′-tetra-O-benzyl-α-D-glucopyranosyl)-D-glucopyranoside

benzyl bromide

2,2',3,3',4',6,6'-hepta-O-benzyl-1β-(p-chlorophenylthio)maltose

Downstream raw materials:

2,2',3,3',4',6,6'-hepta-O-benzyl-N-(<1'',2''-bis(methoxycarbonyl)vinyl>oxy)-D-maltonimido-1,4-lactone

2,2',3,3',4',6,6'-hepta-O-benzyl-N-hydroxy-D-maltonimido-1,4-lactone