4-NITRO-4'-T-BUTYL DIPHENYL ETHER

Base Information

• Chemical Name: 4-NITRO-4'-T-BUTYL DIPHENYL ETHER
• CAS No.: 34859-82-0
• Molecular Formula: C16H17NO3
• Molecular Weight: 271.316
• Hs Code.: 2909309090
• Mol file: 34859-82-0.mol

Synonyms:4-(4-tert-Butylphenoxy)nitrobenzene;4-Nitro-4'-tert-butyldiphenyl ether;4-tert-Butylphenyl 4-nitrophenyl ether;p-tert-Butylphenyl p-nitrophenyl ether;

Chemical Property of 4-NITRO-4'-T-BUTYL DIPHENYL ETHER

Chemical Property:

• Boiling Point: 364.5 °C at 760 mmHg
• Flash Point: 138.3 °C
• PSA: 55.05000
• Density: 1.137 g/cm³
• LogP: 5.20780

Purity/Quality:

95% ^*data from raw suppliers

4-NITRO-4'-T-BUTYL DIPHENYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITRO-4'-T-BUTYL DIPHENYL ETHER

There total 14 articles about 4-NITRO-4'-T-BUTYL DIPHENYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

para-tert-butylphenol (98-54-4) + para-nitrophenyl bromide (586-78-7) → l-(tert-butyl)-4-(4-nitrophenoxy)benzene (34859-82-0)

Guidance literature:

With copper(l) iodide; N,N-dimethylglycine hydrochoride; caesium carbonate; In 1,4-dioxane; at 90 ℃; for 20h;

DOI:10.1021/ol0350947

Reference yield: 95.0%

para-tert-butylphenol (98-54-4) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → l-(tert-butyl)-4-(4-nitrophenoxy)benzene (34859-82-0)

Guidance literature:

With cesium fluoride/clinoptilolite; In dimethyl sulfoxide; at 110 ℃; for 0.5h;

DOI:10.1139/cjc-2015-0300

Reference yield: 91.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + p-tert-butylphenylboronic acid (123324-71-0) → l-(tert-butyl)-4-(4-nitrophenoxy)benzene (34859-82-0)

Guidance literature:

With nickel(II) ferrite; caesium carbonate; In 1,4-dioxane; for 10h; Reflux;

DOI:10.1002/adsc.201300686

upstream raw materials:

para-tert-butylphenol

para-nitrophenyl perfluorobutanesulfonate

4-chlorobenzonitrile

para-nitrophenyl bromide

Downstream raw materials:

4-(4-(tert-butyl)phenoxy)aniline

4-nitro-phenol

para-tert-butylphenol

Refernces

• 1、 -. "Inhibitors of notch signalling pathway and use thereof in treatment of cancers". Page/Page column 39; 41. . Retrieved 2016/04/26.
• 2、 Sharma, Rakesh K.,Gaur, Rashmi,Yadav, Manavi,Rathi, Anuj K.,Pechousek, Jiri,Petr, Martin,Zboril, Radek,Gawande, Manoj B.. "Maghemite-Copper Nanocomposites: Applications for Ligand-Free Cross-Coupling (C-O, C-S, and C-N) Reactions". . p. 3495 - 3502. Retrieved 2015/11/10.