N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Base Information

Chemical Name:N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine
CAS No.:1075253-43-8
Molecular Formula:C₂₇H₂₉F₆N₅OSSi
Molecular Weight:613.702
Hs Code.:

Synonyms:N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Suppliers and Price of N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

There total 1 articles about N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1075253-42-7
2-chloro-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]pyridine

: 367-71-5
2,4-bis(trifluoromethyl)aniline

: 1075253-43-8
N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2-(dicyclohexylphosphino)-2'-methylbiphenyl; In 1,2-dimethoxyethane; at 20 - 100 ℃; under 1344.62 Torr; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm800743q

Reference yield: 50.0%

: 1075253-43-8
N-[2,4-bis(trifluoromethyl)phenyl]-3-(([(1,1-dimethylethyl)(dimethyl)silyl]oxy)methyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

: 1075253-44-9
(2-([2,4-bis(trifluoromethyl)phenyl]amino)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-3-pyridinyl)methanol

Guidance literature:: With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 20 ℃; for 15h; Inert atmosphere;
DOI:10.1021/jm800743q