Technology Process of 2-Methylene-(20S)-19-nor-1alpha-hydroxy-trishomopregnacalciferol
There total 21 articles about 2-Methylene-(20S)-19-nor-1alpha-hydroxy-trishomopregnacalciferol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
- Guidance literature:
-
Multi-step reaction with 10 steps
1: sodium hydrogencarbonate
2: triethylamine
3: dimethyl sulfoxide
4: diisobutylaluminium hydride
5: n-butyllithium
6: hydrogen / palladium on activated charcoal
7: tetrabutyl ammonium fluoride
8: pyridinium chlorochromate
9: n-butyllithium
10: tetrabutyl ammonium fluoride / tetrahydrofuran
With
n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; diisobutylaluminium hydride; sodium hydrogencarbonate; triethylamine; pyridinium chlorochromate;
palladium on activated charcoal;
In
tetrahydrofuran; dimethyl sulfoxide;
9: Wittig-Horner coupling;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: triethylamine
2: dimethyl sulfoxide
3: diisobutylaluminium hydride
4: n-butyllithium
5: hydrogen / palladium on activated charcoal
6: tetrabutyl ammonium fluoride
7: pyridinium chlorochromate
8: n-butyllithium
9: tetrabutyl ammonium fluoride / tetrahydrofuran
With
n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; diisobutylaluminium hydride; triethylamine; pyridinium chlorochromate;
palladium on activated charcoal;
In
tetrahydrofuran; dimethyl sulfoxide;
8: Wittig-Horner coupling;
