Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Base Information

Chemical Name:Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂
CAS No.:116246-69-6
Molecular Formula:C₄₁H₅₂N₆O₇
Molecular Weight:740.9
Hs Code.:

Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH<sub>2</sub>

Synonyms:Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Suppliers and Price of Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

There total 10 articles about Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 116246-68-5
Ppoc-Phe-D-Trp(Boc)-Leu-OMe

: 116246-69-6
Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Guidance literature:: With hydrazine hydrate; In methanol; Ambient temperature;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 116246-69-6
Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Guidance literature:: Multi-step reaction with 6 steps

1: 99 percent / 4-dimethylaminopyridine / acetonitrile / 2 h

2: 4.46 g / trifluoroacetic acid / CH₂Cl₂ / 1 h

3: 93 percent / CH₂Cl₂ / from -10 deg C to r.t.

4: 100 percent / hydrazine hydrate / methanol / 2 h / Ambient temperature

5: 1.) HCl, isopentyl nitrite; 2.) N-methyl-morpholine / 1.) DMF, dioxane, 30 min, -30 deg C; 2.) DMF, dioxane, 2 h, -15 deg C then r.t., pH 7.5, overnight

6: 86 percent / hydrazine hydrate / methanol / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; dmap; hydrazine hydrate; trifluoroacetic acid; isopentyl nitrite; In methanol; dichloromethane; acetonitrile;

Reference yield:

: 96572-82-6
Methyl 1-(tert-butyloxycarbonyl)-D-tryptophanate

: 116246-69-6
Ppoc-Phe-D-Trp(Boc)-Leu-NH-NH₂

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / CH₂Cl₂ / from -10 deg C to r.t.

2: 100 percent / hydrazine hydrate / methanol / 2 h / Ambient temperature

3: 1.) HCl, isopentyl nitrite; 2.) N-methyl-morpholine / 1.) DMF, dioxane, 30 min, -30 deg C; 2.) DMF, dioxane, 2 h, -15 deg C then r.t., pH 7.5, overnight

4: 86 percent / hydrazine hydrate / methanol / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; hydrazine hydrate; isopentyl nitrite; In methanol; dichloromethane;