(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

Base Information

Chemical Name:(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate
CAS No.:1135467-15-0
Molecular Formula:C₂₂H₂₅N₃O₃
Molecular Weight:379.459
Hs Code.:

Synonyms:(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

Suppliers and Price of (S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

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Technology Process of (S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

There total 1 articles about (S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 269085-45-2
benzyl (S)-1-(1H-imidazol-4-yl)-2-phenylethylcarbamate

: 3188-13-4
ethyl chloromethyl ether

: 1135467-31-0
(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-5-yl]-2-phenylethylcarbamate

: 1135467-15-0
(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 25 ℃; for 2h; optical yield given as %ee;
DOI:10.1055/s-0028-1083263

Reference yield: 66.0%

: 108-86-1,52753-63-6
bromobenzene

: 1135467-15-0
(S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate

: 1135467-18-3
(S)-benzyl 1-[1-(ethoxymethyl)-2-phenyl-1H-imidazol-4-yl]-2-phenylethylcarbamate

Guidance literature:: (S)-benzyl 1-[1-(ethoxymethyl)-1H-imidazol-4-yl]-2-phenylethylcarbamate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h; Inert atmosphere;

With zinc dibromide; In tetrahydrofuran; hexane; at -78 - 25 ℃; Inert atmosphere;

bromobenzene; optical yield given as %ee; Further stages;
DOI:10.1055/s-0028-1083263