6-chloro-5-nitro-3-pyridyl phenyl ketone

Base Information

• Chemical Name: 6-chloro-5-nitro-3-pyridyl phenyl ketone
• CAS No.: 132680-59-2
• Molecular Formula: C₁₂H₇ClN₂O₃
• Molecular Weight: 262.652
• Mol file: 132680-59-2.mol

Synonyms:6-chloro-5-nitro-3-pyridyl phenyl ketone

Chemical Property of 6-chloro-5-nitro-3-pyridyl phenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 6-chloro-5-nitro-3-pyridyl phenyl ketone

There total 1 articles about 6-chloro-5-nitro-3-pyridyl phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-hydroxy-5-nitronicotinic acid (6635-31-0) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 6-chloro-5-nitro-3-pyridyl phenyl ketone (132680-59-2)

Guidance literature:

With aluminium trichloride; phosphorus pentachloride; Yield given. Multistep reaction; 1.a) 7 h, reflux b) 18 h, r.t. 2.) 1.5 h, reflux;

DOI:10.1002/jhet.5570270656

Reference yield: 83.0%

6-chloro-5-nitro-3-pyridyl phenyl ketone (132680-59-2) → 6-amino-5-nitro-3-pyridyl phenyl ketone (132680-60-5)

Guidance literature:

With ammonium hydroxide; In methanol; for 2.5h; Heating;

DOI:10.1002/jhet.5570270656

upstream raw materials:

6-hydroxy-5-nitronicotinic acid

benzene

Downstream raw materials:

6-amino-5-nitro-3-pyridyl phenyl ketone