6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

Base Information

Chemical Name:6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt
CAS No.:910643-37-7
Molecular Formula:C₁₂H₆F₂NO₃*Na
Molecular Weight:273.171
Hs Code.:

Synonyms:6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

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Chemical Property of 6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

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Technology Process of 6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

There total 2 articles about 6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910643-36-6
methyl 6-(2,4-difluorophenoxy)nicotinate

: 910643-37-7
6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

Guidance literature:: With methanol; sodium hydroxide; water; In tetrahydrofuran; for 4h; Heating / reflux;

Reference yield:

: 73781-91-6
6-Chloronicotinic acid methyl ester

: 367-27-1
2,4-difluorophenol

: 910643-37-7
6-(2,4-difluoro-phenoxy)-nicotinic acid sodium salt

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 100 °C

2: methanol; sodium hydroxide; water / tetrahydrofuran / 4 h / Heating / reflux

With methanol; sodium hydroxide; water; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;