1-(3-Fluorophenyl)cyclopropanecarboxylic acid

Base Information

Chemical Name:1-(3-Fluorophenyl)cyclopropanecarboxylic acid
CAS No.:248588-33-2
Molecular Formula:C10H9 F O2
Molecular Weight:180.179
Hs Code.:2916200090
DSSTox Substance ID:DTXSID80424422
Mol file:248588-33-2.mol

Synonyms:248588-33-2;1-(3-fluorophenyl)cyclopropanecarboxylic acid;1-(3-fluorophenyl)cyclopropane-1-carboxylic acid;1-(3-Fluoro-phenyl)-cyclopropanecarboxylic acid;MFCD07374443;1-(3-Fluorophenyl)cyclopropanecarboxylicacid;SCHEMBL301111;DTXSID80424422;AKOS000126099;AB39477;FS-2341;SY079651;CS-0060402;FT-0677910;EN300-78358;1-(3-Fluorophenyl)-cyclopropanecarboxylic acid;E10043;Cyclopropanecarboxylic acid, 1-(3-fluorophenyl)-;Z361883656;1-(3-Fluorophenyl)cyclopropanecarboxylic acid, AldrichCPR

Suppliers and Price of 1-(3-Fluorophenyl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Fluorophenyl)cyclopropanecarboxylicacid
50mg
$ 45.00

SynQuest Laboratories
1-(3-Fluorophenyl)-cyclopropanecarboxylic acid 95.0%
250 mg
$ 168.00

Matrix Scientific
1-(3-Fluoro-phenyl)-cyclopropanecarboxylic acid
500mg
$ 182.00

Crysdot
1-(3-Fluorophenyl)cyclopropanecarboxylicacid 95+%
5g
$ 669.00

ChemScene
1-(3-Fluorophenyl)cyclopropane-1-carboxylicacid >97.0%
250mg
$ 90.00

ChemScene
1-(3-Fluorophenyl)cyclopropane-1-carboxylicacid >97.0%
100mg
$ 55.00

ChemScene
1-(3-Fluorophenyl)cyclopropane-1-carboxylicacid >97.0%
1g
$ 180.00

Chemenu
1-(3-Fluoro-phenyl)-cyclopropanecarboxylicacid 95%+
5g
$ 1030.00

Atlantic Research Chemicals
1-(3-Fluorophenyl)cyclopropanecarboxylicacid 95%
1gm:
$ 279.23

Anichem
1-(3-Fluoro-phenyl)-cyclopropanecarboxylicacid >95%
1g
$ 180.00

Total 14 raw suppliers

Chemical Property of 1-(3-Fluorophenyl)cyclopropanecarboxylic acid

Chemical Property:

Vapor Pressure:0.000199mmHg at 25°C
Refractive Index:1.584
Boiling Point:314.3°C at 760 mmHg
Flash Point:143.9°C
Density:1.361g/cm³
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:180.05865769
Heavy Atom Count:13
Complexity:223

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Fluorophenyl)cyclopropanecarboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1(C2=CC(=CC=C2)F)C(=O)O

Technology Process of 1-(3-Fluorophenyl)cyclopropanecarboxylic acid

There total 3 articles about 1-(3-Fluorophenyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.7%

: 124276-55-7
1-(3-fluorophenyl)cyclopropane-1-carbonitrile

: 248588-33-2
1-(3-fluorophenyl)cyclopropane-1-carboxylic acid

Guidance literature:: With water; potassium hydroxide; In ethanol; for 24h; Reflux;

Reference yield:

: 501-00-8
3-fluorophenylacetonitrile

: 107-04-0
1-Bromo-2-chloroethane

: 248588-33-2
1-(3-fluorophenyl)cyclopropane-1-carboxylic acid

Guidance literature:: 3-fluorophenylacetonitrile; 1-Bromo-2-chloroethane; With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In water; at 40 ℃; for 3h;

In water; ethylene glycol; at 100 ℃; for 20h;

Reference yield:

: 501-00-8
3-fluorophenylacetonitrile

: 248588-33-2
1-(3-fluorophenyl)cyclopropane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide / water / 12 h / 50 °C

2: lithium hydroxide / water; ethylene glycol / 24 h / 100 °C

With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; lithium hydroxide; In water; ethylene glycol;
DOI:10.1021/jacs.9b04549