1-(3-Fluorophenyl)cyclopropanecarbonitrile

Base Information

• Chemical Name: 1-(3-Fluorophenyl)cyclopropanecarbonitrile
• CAS No.: 124276-55-7
• Molecular Formula: C10H8 F N
• Molecular Weight: 161.179
• European Community (EC) Number: 840-938-5
• DSSTox Substance ID: DTXSID80601776
• Wikidata: Q82498594
• Mol file: 124276-55-7.mol

Synonyms:1-(3-FLUOROPHENYL)CYCLOPROPANECARBONITRILE;124276-55-7;1-(3-FLUOROPHENYL)CYCLOPROPANE-1-CARBONITRILE;CYCLOPROPANECARBONITRILE, 1-(3-FLUOROPHENYL)-;MFCD07374415;Cyclopropanecarbonitrile, 1-(3-fluorophenyl)- (9CI);SCHEMBL10526309;DTXSID80601776;AKOS000265644;AB39403;AS-41487;SY088924;1-(3-fluorophenyl)cyclopropane carbonitrile;DB-345225;CS-0088419;EN300-312479;A920468;Z361883082

Chemical Property of 1-(3-Fluorophenyl)cyclopropanecarbonitrile

Chemical Property:

• PSA: 23.79000
• LogP: 2.38088
• Storage Temp.: 2-8°C
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 161.064077422
• Heavy Atom Count: 12
• Complexity: 223

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Fluorophenyl)cyclopropanecarbonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1(C#N)C2=CC(=CC=C2)F

Technology Process of 1-(3-Fluorophenyl)cyclopropanecarbonitrile

There total 2 articles about 1-(3-Fluorophenyl)cyclopropanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-fluorophenylacetonitrile (501-00-8) + 1-Bromo-2-chloroethane (107-04-0) → 1-(3-fluorophenyl)cyclopropane-1-carbonitrile (124276-55-7)

Guidance literature:

3-fluorophenylacetonitrile; With sodium hydride; In N,N-dimethyl acetamide; mineral oil; at -15 - -10 ℃; for 0.25h; Inert atmosphere;

1-Bromo-2-chloroethane; In N,N-dimethyl acetamide; mineral oil; at -10 - 20 ℃; for 1h;

Reference yield:

3-fluorophenylacetonitrile (501-00-8) + ethylene dibromide (106-93-4) → 1-(3-fluorophenyl)cyclopropane-1-carbonitrile (124276-55-7)

Guidance literature:

3-fluorophenylacetonitrile; With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

ethylene dibromide; In dimethyl sulfoxide; for 5h;

Reference yield: 93.7%

1-(3-fluorophenyl)cyclopropane-1-carbonitrile (124276-55-7) → 1-(3-fluorophenyl)cyclopropane-1-carboxylic acid (248588-33-2)

Guidance literature:

With water; potassium hydroxide; In ethanol; for 24h; Reflux;

upstream raw materials:

3-fluorophenylacetonitrile

ethylene dibromide

1-Bromo-2-chloroethane

Downstream raw materials:

1-(3-fluorophenyl)cyclopropyl methylamine

C₂₂H₂₀FN₃O₅

1-(3-fluorophenyl)cyclopropane-1-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 124276-55-7 Cyclopropanecarbonitrile, 1-(3-fluorophenyl)- (9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send