1,1-Cyclopropanedicarbonyl chloride

Base Information

• Chemical Name: 1,1-Cyclopropanedicarbonyl chloride
• CAS No.: 34782-60-0
• Molecular Formula: C5H4 Cl2 O2
• Molecular Weight: 166.992
• Hs Code.: 2917209090
• DSSTox Substance ID: DTXSID10575810
• Nikkaji Number: J2.822.460E
• Wikidata: Q82465229
• Mol file: 34782-60-0.mol

Synonyms:34782-60-0;1,1-cyclopropanedicarbonyl chloride;cyclopropane-1,1-dicarbonyl chloride;1,1-Cyclopropanedicarbonyl dichloride (9CI);1,1-CYCLOPROPANEDICARBONYL DICHLORIDE;SCHEMBL808920;DTXSID10575810;Cyclopropane-1,1-dicarbonyl dichloride

Chemical Property of 1,1-Cyclopropanedicarbonyl chloride

Chemical Property:

• Boiling Point: 78-80 °C(Press: 15 Torr)
• PSA: 34.14000
• Density: 1.606±0.06 g/cm3(Predicted)
• LogP: 1.29740
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 165.9588348
• Heavy Atom Count: 9
• Complexity: 156

Purity/Quality:

99%, ^*data from raw suppliers

1,1-Cyclopropanedicarbonyldichloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1(C(=O)Cl)C(=O)Cl

Technology Process of 1,1-Cyclopropanedicarbonyl chloride

There total 1 articles about 1,1-Cyclopropanedicarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

cyclopropane-1,1-dicarboxylic acid (598-10-7) → cyclopropane-1,1-dicarboxylic acid dichloride (34782-60-0)

Guidance literature:

With phosphorus pentachloride; In Petroleum ether; Heating;

Reference yield: 90.0%

(1S,2R)-2-Amino-1,2-diphenylethanol (23364-44-5) + cyclopropane-1,1-dicarboxylic acid dichloride (34782-60-0) → N,N'-bis((1R,2S)-2-hydroxy-1,2-diphenylethyl)cyclopropane-1,1-dicarboxamide

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201906754

Reference yield: 80.0%

cyclopropane-1,1-dicarboxylic acid dichloride (34782-60-0) + 3-fluoro-4-[6-methoxy-7-(piperidin-4-ylmethoxy)quinoline-4-oxy]aniline (1201940-00-2) → C27H27ClFN3O5

Guidance literature:

In tetrahydrofuran;

upstream raw materials:

cyclopropane-1,1-dicarboxylic acid

Downstream raw materials:

3-Phenyl-1,2,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazin-6-spiro-1'-cyclopropan-2,5,7-trion

3-Cyclohexyl-1,2,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazin-6-spiro-1'-cyclopropan-2,5,7-trion

2,3-Dihydro-6-(4-methylphenyl)-4H-furo<3,2-c>pyran-4-on

2,3-Dihydro-6-(4-methoxyphenyl)-4H-furo<3,2-c>pyran-4-on