1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole

Base Information

• Chemical Name: 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole
• CAS No.: 1514928-03-0
• Molecular Formula: C₁₆H₁₅N₃O₃S
• Molecular Weight: 329.379
• Mol file: 1514928-03-0.mol

Synonyms:1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole

Chemical Property of 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole

There total 1 articles about 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-toluenesulfonyl azide (941-55-9) + 1-ethynyl-2-methoxybenzene (767-91-9) → 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole (1514928-03-0)

Guidance literature:

With (N,N’-bis-{2,6-(di-iso-propyl)phenyl}imidazole-2-ylidene)tri-tert-butylphosphinetetrafluoroborate copper (I); In toluene; at 20 ℃; for 15h;

DOI:10.1021/acs.organomet.7b00506

Reference yield: 91.0%

Quinoline N-oxide (1613-37-2) + 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole (1514928-03-0) → 2-(4-(2-methoxyphenyl)-1H-1,2,3-triazol-1-yl)quinoline

Guidance literature:

In 1,2-dichloro-ethane; at 20 ℃; regioselective reaction; Inert atmosphere;

DOI:10.3762/BJOC.17.42

Reference yield: 88.0%

2-hydroxy-2,4,6-cycloheptatrien-1-one (533-75-5) + 1-(4-methylbenzenesulfonyl)-4-(2-methoxybenzene)-1H-1,2,3-triazole (1514928-03-0) → N-[2-(2-methoxyphenyl)-2-oxoethyl]-4-methyl-N-(7-oxocyclohepta-1,3,5-trienyl)benzenesulfonamide

Guidance literature:

With dirhodium tetraacetate; In 1,2-dichloro-ethane; at 80 ℃; for 1h; Inert atmosphere;

DOI:10.1002/adsc.201500829

upstream raw materials:

4-toluenesulfonyl azide

1-ethynyl-2-methoxybenzene

Downstream raw materials:

3-butyl-4-(2-methoxyphenyl)-1-tosyl-1H-pyrrol-2(5H)-one