phenylacetic acid 3-phenylprop-2-ynyl ester

Base Information

• Chemical Name: phenylacetic acid 3-phenylprop-2-ynyl ester
• CAS No.: 282103-93-9
• Molecular Formula: C₁₇H₁₄O₂
• Molecular Weight: 250.297
• Mol file: 282103-93-9.mol

Synonyms:phenylacetic acid 3-phenylprop-2-ynyl ester

Chemical Property of phenylacetic acid 3-phenylprop-2-ynyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of phenylacetic acid 3-phenylprop-2-ynyl ester

There total 2 articles about phenylacetic acid 3-phenylprop-2-ynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

phenylacetic acid (103-82-2) + 3-Phenyl-2-propyn-1-ol (1504-58-1) → phenylacetic acid 3-phenylprop-2-ynyl ester (282103-93-9)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 25 ℃;

DOI:10.1021/jo991938h

Reference yield: 56.0%

3-Phenyl-2-propyn-1-ol (1504-58-1) + phenylacetyl chloride (103-80-0) → phenylacetic acid 3-phenylprop-2-ynyl ester (282103-93-9)

Guidance literature:

With pyridine; dmap; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol9016782

Reference yield: 84.0%

phenylacetic acid 3-phenylprop-2-ynyl ester (282103-93-9) → diazophenylacetic acid 3-phenylprop-2-ynyl ester (282103-94-0)

Guidance literature:

With sodium hydride; azidotris(diethylamino)phosphonium bromide; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1021/jo991938h

upstream raw materials:

phenylacetic acid

3-Phenyl-2-propyn-1-ol

phenylacetyl chloride

Downstream raw materials:

diazophenylacetic acid 3-phenylprop-2-ynyl ester

C₁₇H₁₅FO₂

C₁₇H₁₅FO₂

phenyl(3-phenylfuran-2-yl)methanone