2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE

Base Information

Chemical Name:2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE
CAS No.:34637-40-6
Molecular Formula:C₉H₈N₂O₂
Molecular Weight:176.175
Hs Code.:2933990090
Mol file:34637-40-6.mol

Synonyms:4(1H)-Quinazolinone,2-(hydroxymethyl)- (8CI,9CI); 4(3H)-Quinazolinone, 2-(hydroxymethyl)- (7CI);2-(Hydroxymethyl)-4(3H)-quinazolinone; 2-Quinazolinemethanol, 4-hydroxy-

Suppliers and Price of 2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(hydroxymethyl)-4(3H)-quinazolinonehydrochloride
50mg
$ 45.00

American Custom Chemicals Corporation
2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE 95.00%
1G
$ 692.46

American Custom Chemicals Corporation
2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE 95.00%
5G
$ 1759.28

AK Scientific
2-(Hydroxymethyl)quinazolin-4(3h)-one
10g
$ 1274.00

AK Scientific
2-(Hydroxymethyl)quinazolin-4(3h)-one
100mg
$ 241.00

Total 1 raw suppliers

Chemical Property of 2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE

Chemical Property:

Vapor Pressure:3.89E-06mmHg at 25°C
Refractive Index:1.675
Boiling Point:370.3°Cat760mmHg
Flash Point:177.7°C
PSA：66.24000
Density:1.41g/cm³
LogP:0.82770

Purity/Quality:: 2-(hydroxymethyl)-4(3H)-quinazolinonehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE

There total 9 articles about 2-(HYDROXYMETHYL)QUINAZOLIN-4(3H)-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 21721-76-6
2-methoxymethylquinazolin-4(3H)-one

: 34637-40-6
2-(hydroxymethyl)quinazolin-4(3H)-one

Guidance literature:: With hydrogen bromide; In water;
DOI:10.1021/jm401394u

Reference yield: 81.0%

: 129768-44-1
2-(α-Acetoxyacetyl)aminobenzamide

: 34637-40-6
2-(hydroxymethyl)quinazolin-4(3H)-one

Guidance literature:: With potassium hydroxide; at 80 ℃; for 1h;
DOI:10.1016/S0040-4020(01)86694-1

Reference yield:

: 219739-45-4
2-methoxyacetamidobenzonitrile

: 34637-40-6
2-(hydroxymethyl)quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / urea hydrogen peroxide; K₂CO₃ / acetone; H₂O / 50 h / 82 °C

2: 61 percent / aq. HBr, 48 percent / 11 h / Heating

With urea hydrogen peroxide; hydrogen bromide; potassium carbonate; In water; acetone; 1: Oxidation / 2: Hydrolysis;
DOI:10.1080/00397919808004519