1,18-Octadecanediol

Base Information

• Chemical Name: 1,18-Octadecanediol
• CAS No.: 3155-43-9
• Molecular Formula: C18H38O2
• Molecular Weight: 286.499
• Hs Code.: 2905399090
• Mol file: 3155-43-9.mol

Synonyms:1,18-octadecanediol;Octadecane-1,18-diol

Chemical Property of 1,18-Octadecanediol

Chemical Property:

• Vapor Pressure: 5.77E-08mmHg at 25°C
• Melting Point: 91°C
• Refractive Index: 1.464
• Boiling Point: 397.4 °C at 760 mmHg
• PKA: 14.90±0.10(Predicted)
• Flash Point: 169.1 °C
• PSA: 40.46000
• Density: 0.893 g/cm³
• LogP: 5.21260
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

1,18-Octadecanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Octadecane-1,18-diol is a useful research chemical compound.

Technology Process of 1,18-Octadecanediol

There total 24 articles about 1,18-Octadecanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethyl 1,18-octadecanedioate (1472-93-1) → octadecane-1,18-diol (3155-43-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Reflux; Inert atmosphere;

DOI:10.1021/acsmedchemlett.9b00477

Reference yield: 94.0%

octadecanedioic acid (871-70-5) → octadecane-1,18-diol (3155-43-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Reflux;

DOI:10.1002/jlcr.3885

Reference yield: 87.0%

C32H42O2 (1029587-87-8) → octadecane-1,18-diol (3155-43-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 ℃; for 72h; under 38002.6 Torr;

DOI:10.1016/j.tet.2008.02.054

upstream raw materials:

18-acetoxy-octadecanoic acid methyl ester

dimethyl 1,18-octadecanedioate

diethyl octadecanedioate

methanol

Downstream raw materials:

1-(18-iodooctadecyl)-4-methoxybenzene

1-eicos-19-ynyl-4-methoxybenzene

1-methoxy-4-(19-methyleicos-19-enyl)benzene

18-bromooctadecan-1-ol

Refernces

• 1、 Schink, Carina,Spielvogel, Sandra,Imhof, Wolfgang. "Synthesis of 13C-labelled cutin and suberin monomeric dicarboxylic acids of the general formula HO213C-(CH2)n-13CO2H (n = 10, 12, 14, 16, 18, 20, 22, 24, 26, 28)". . p. 14 - 29. Retrieved 2020/11/30.
• 2、 Wang, Kaiya,Cai, Xiaoyang,Yao, Wei,Tang, Du,Kataria, Rhea,Ashbaugh, Henry S.,Byers, Larry D,Gibb, Bruce C.. "Electrostatic Control of Macrocyclization Reactions within Nanospaces". supporting information. p. 6740 - 6747. Retrieved 2019/05/06.