2-methoxy-5,6,7,8-tetrafluoronaphthalene

Base Information

• Chemical Name: 2-methoxy-5,6,7,8-tetrafluoronaphthalene
• CAS No.: 256479-34-2
• Molecular Formula: C₁₁H₆F₄O
• Molecular Weight: 230.162
• Mol file: 256479-34-2.mol

Synonyms:2-methoxy-5,6,7,8-tetrafluoronaphthalene

Chemical Property of 2-methoxy-5,6,7,8-tetrafluoronaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-5,6,7,8-tetrafluoronaphthalene

There total 1 articles about 2-methoxy-5,6,7,8-tetrafluoronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

3-methoxy-thiophene (17573-92-1) + 1-chloro-2,3,4,5,6-pentafluorobenzene (344-07-0) → octafluorodibenzothiophene (7136-57-4) + 2-methoxy-5,6,7,8-tetrafluoronaphthalene (256479-34-2)

Guidance literature:

1-chloro-2,3,4,5,6-pentafluorobenzene; With n-butyllithium; In hexane; at -15 ℃;

3-methoxy-thiophene; In hexane; at -15 - 20 ℃; for 12h;

DOI:10.1021/ol991244v

Reference yield: 80.0%

diphenylphosphane (829-85-6) + 2-methoxy-5,6,7,8-tetrafluoronaphthalene (256479-34-2) → C23H16F3OP

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 5h;

DOI:10.1016/j.tetlet.2007.09.016

Reference yield: 60.0%

2-methoxy-5,6,7,8-tetrafluoronaphthalene (256479-34-2) + dicyclohexylphosphine borane complex → C23H28F3OP*BH3

Guidance literature:

With n-butyllithium; for 16h; Heating;

DOI:10.1016/j.tetlet.2007.09.016

upstream raw materials:

3-methoxy-thiophene

1-chloro-2,3,4,5,6-pentafluorobenzene

Refernces