1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Base Information

Chemical Name:1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid
CAS No.:245064-80-6
Molecular Formula:C14H10 N2 O4 S
Molecular Weight:302.31
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50579231
Nikkaji Number:J1.150.202D
Wikidata:Q82469698
Mol file:245064-80-6.mol

Synonyms:245064-80-6;1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid;1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID, 1-(PHENYLSULFONYL)-;1-(BENZENESULFONYL)PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID;DTXSID50579231;1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylicacid;CS-0004234;1-(Benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Suppliers and Price of 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylicacid 95+%
1g
$ 772.00

Chemenu
1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylicacid 95%
1g
$ 729.00

American Custom Chemicals Corporation
1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 95.00%
5MG
$ 499.40

Alichem
1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylicacid
1g
$ 690.80

Total 3 raw suppliers

Chemical Property of 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Chemical Property:

Vapor Pressure:1.26E-14mmHg at 25°C
Refractive Index:1.694
Boiling Point:587.1°C at 760 mmHg
Flash Point:308.8°C
PSA：97.64000
Density:1.49g/cm³
LogP:3.05230
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:302.03612798
Heavy Atom Count:21
Complexity:496

Purity/Quality:

99% ^*data from raw suppliers

1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)N2C=C(C3=C2N=CC=C3)C(=O)O

Technology Process of 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

There total 3 articles about 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 155819-08-2
1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde

: 245064-80-6
1-Phenylsulfonylpyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: With sodium chlorite; aminosulfonic acid; In 1,4-dioxane; water; at 20 ℃; for 0.5h;
DOI:10.1016/S0040-4039(99)01138-7

Reference yield:

: 4649-09-6
1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde

: 245064-80-6
1-Phenylsulfonylpyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / NaH / tetrahydrofuran / 0 °C

2: 95 percent / NaClO₂; NH₂SO₃H / dioxane; H₂O / 0.5 h / 20 °C

With sodium chlorite; aminosulfonic acid; sodium hydride; In tetrahydrofuran; 1,4-dioxane; water; 1: Substitution / 2: Oxidation;
DOI:10.1016/S0040-4039(99)01138-7

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 245064-80-6
1-Phenylsulfonylpyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / NaH / tetrahydrofuran / 0 °C

2: 95 percent / NaClO₂; NH₂SO₃H / dioxane; H₂O / 0.5 h / 20 °C

With sodium chlorite; aminosulfonic acid; sodium hydride; In tetrahydrofuran; 1,4-dioxane; water; 1: Substitution / 2: Oxidation;
DOI:10.1016/S0040-4039(99)01138-7