[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Base Information

Chemical Name:[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide
CAS No.:404942-48-9
Molecular Formula:C₁₈H₁₂FN₃O₂
Molecular Weight:321.311
Hs Code.:

Synonyms:[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Suppliers and Price of [(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

There total 2 articles about [(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 403-43-0
4-fluorobenzoyl chloride

: 404942-39-8
[(3aS,8aR)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

: 404942-48-9
[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1016/S0040-4020(01)00933-4

Reference yield:

: 7480-35-5,13286-59-4,74165-73-4,126456-43-7,136030-00-7,140632-19-5,140632-20-8
(1S,2R)-1-amino-2-indanol

: 404942-48-9
[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / ethanol / Heating

2: 78 percent / Et₃N / CH₂Cl₂ / 48 h / 20 °C

With triethylamine; In ethanol; dichloromethane;
DOI:10.1016/S0040-4020(01)00933-4

Reference yield:

: 618-36-0
rac-methylbenzylamine

: 404942-48-9
[(3aS,8aR)-3-(4-fluorobenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide

: 4-fluoro-N-(1-phenyl-ethyl)-benzamide

: (S)-4-fluoro-N-(1-phenylethyl)benzamide

Guidance literature:: In tetrahydrofuran; acetonitrile; at -70 ℃; for 108h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00933-4