4-((4-Chloropyrimidin-2-yl)amino)benzonitrile

Base Information

Chemical Name:4-((4-Chloropyrimidin-2-yl)amino)benzonitrile
CAS No.:244768-32-9
Molecular Formula:C11H7ClN4
Molecular Weight:230.656
Hs Code.:2933599590
European Community (EC) Number:607-384-4
DSSTox Substance ID:DTXSID90458374
Wikidata:Q72458934
Mol file:244768-32-9.mol

Synonyms:244768-32-9;4-((4-Chloropyrimidin-2-yl)amino)benzonitrile;4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile;Benzonitrile, 4-[(4-chloro-2-pyrimidinyl)amino]-;4-[(4-chloropyrimidin-2-yl)amino]benzonitrile;4-(4-chloropyrimidin-2-ylamino)benzonitrile;4-N[2(4-CHLOROPYRIMIDINYL)]AMINO BENZONITRILE;4-[(4-Chloro-2-pyrimidinyl)amino]-benzonitrile;4-(4-chloro-pyrimidin-2-ylamino)benzonitrile;EC 607-384-4;4-((4-chloro-2-pyrimidinyl)amino)benzonitrile;4-[(4-chloro-2-pyrimidinyl)amino)benzonitrile;Rilpivirine Chloro Impurity;SCHEMBL867999;DTXSID90458374;QXCHAADSAYQDHL-UHFFFAOYSA-N;BCP23055;CL4549;MFCD08443699;AKOS015917905;CS-O-31749;HE-0022;AC-27707;A5035;C3284;CS-0006975;FT-0664940;4-(4-chloropyrimidin-2-ylamino)-benzonitrile;4-[(4chloro-2-pyrimidinyl)amino]benzonitrile;4[(4-chloro-2-pyrimidinyl)amino]benzonitrile;4-(4-Chloro-pyrimidin-2-ylamino)-benzonitrile;4-N[2(4-chloropyrimidinyl)]-amino benzonitrile;4-[(4-chloropyrimidin-2-yl)amino]benzonitrile =;A1-04830;W-206895

Suppliers and Price of 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-(4-Chloropyrimidin-2-ylamino)benzonitrile
25g
$ 768.00

Alichem
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile
25g
$ 601.72

Alichem
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile
10g
$ 334.40

Alichem
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile
5g
$ 169.60

Ambeed
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile 97%
1g
$ 87.00

Ambeed
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile 97%
5g
$ 264.00

Ambeed
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile 97%
25g
$ 791.00

American Custom Chemicals Corporation
4-N[2(4-CHLOROPYRIMIDINYL)]AMINO BENZONITRILE 98.00%
1G
$ 210.00

AstaTech
4-[(4-CHLORO-2-PYRIMIDINYL)AMINO]BENZONITRILE 97%
5 / G
$ 207.00

AstaTech
4-[(4-CHLORO-2-PYRIMIDINYL)AMINO]BENZONITRILE 97%
1 / G
$ 69.00

Total 82 raw suppliers

Chemical Property of 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile

Chemical Property:

Vapor Pressure:5.63E-08mmHg at 25°C
Melting Point:210 °C(dec.)
Refractive Index:1.649
Boiling Point:441°Cat760mmHg
PKA:2.15±0.10(Predicted)
Flash Point:220.5°C
PSA：61.60000
Density:1.39g/cm³
LogP:2.81828
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:Methanol
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:230.0359239
Heavy Atom Count:16
Complexity:266

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Chloropyrimidin-2-ylamino)benzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C#N)NC2=NC=CC(=N2)Cl
Uses 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is used in the preparation of 2-naphthyl substituted diarylpyrimidines (DAPY) analogues.

Technology Process of 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile

There total 10 articles about 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.9%

: 189956-45-4
4-[(4-hydroxy-2-pyrimidinyl)amino]benzonitrile

: 244768-32-9
4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile

Guidance literature:: With triethylamine; trichlorophosphate; at 0 - 95 ℃;

Reference yield: 82.0%

: 2-methylthio-4-pyrimidone

: 873-74-5
4-Aminobenzonitrile

: 244768-32-9
4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile

Guidance literature:: 2-methylthio-4-pyrimidone; 4-Aminobenzonitrile; at 180 - 190 ℃; for 8h;

With trichlorophosphate; for 1h; Reflux;
DOI:10.1016/j.ejmech.2018.01.016