N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Base Information

Chemical Name:N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride
CAS No.:1403472-94-5
Molecular Formula:C₂₁H₁₇ClN₄O₄*ClH
Molecular Weight:461.304
Hs Code.:

Synonyms:N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Suppliers and Price of N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

There total 4 articles about N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1403473-45-9
N-{3-[3-(tert-butoxycarbonylamino)benzyl]-2,4-dioxoimidazolidin-1-yl}-5-(3-chlorophenyl)-2-furamide

: 1403472-94-5
N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃; for 3h;
DOI:10.1016/j.bmc.2012.08.062

Reference yield:

: 22078-59-7
5-(3-chlorophenyl)-2-furancarboxaldehyde

: 1403472-94-5
N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium dihydrogenphosphate; 2-methyl-but-2-ene; sodium chlorite / water; tert-butyl alcohol / 11 h / 20 °C

2.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; 4-methyl-morpholine / water; methanol / 19 h / 20 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 0 - 20 °C / Inert atmosphere

3.2: 4 h / 0 - 20 °C / Inert atmosphere

4.1: hydrogenchloride / ethyl acetate / 3 h / 0 - 20 °C

With 4-methyl-morpholine; hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; potassium carbonate; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; water; ethyl acetate; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.bmc.2012.08.062

Reference yield:

: 41019-44-7
5-(3-chlorophenyl) furan-2-carboxylic acid

: 1403472-94-5
N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-(3-chlorophenyl)-2-furamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; 4-methyl-morpholine / water; methanol / 19 h / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 0 - 20 °C / Inert atmosphere

2.2: 4 h / 0 - 20 °C / Inert atmosphere

3.1: hydrogenchloride / ethyl acetate / 3 h / 0 - 20 °C

With 4-methyl-morpholine; hydrogenchloride; potassium carbonate; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.08.062