(4-AMINOMETHYL)BENZYL ALCOHOL HCL

Base Information

• Chemical Name: (4-AMINOMETHYL)BENZYL ALCOHOL HCL
• CAS No.: 34403-46-8
• Molecular Formula: C8H11 N O . Cl H
• Molecular Weight: 173.642
• Hs Code.: 2922199090
• Mol file: 34403-46-8.mol

Synonyms:Benzenemethanol,4-(aminomethyl)-, hydrochloride (9CI); Benzyl alcohol, p-(aminomethyl)-,hydrochloride (6CI,8CI); [4-(Aminomethyl)phenyl]methanol hydrochloride

Chemical Property of (4-AMINOMETHYL)BENZYL ALCOHOL HCL

Chemical Property:

• Vapor Pressure: 0.00185mmHg at 25°C
• Boiling Point: 280°Cat760mmHg
• Flash Point: 123.2°C
• PSA: 46.25000
• Density: g/cm³
• LogP: 2.13990
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

(4-Aminomethyl)benzylAlcoholHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (4-Aminomethyl)benzyl alcohol HCl

Technology Process of (4-AMINOMETHYL)BENZYL ALCOHOL HCL

There total 9 articles about (4-AMINOMETHYL)BENZYL ALCOHOL HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-cyanobenzaldehyde (105-07-7) → [4-(amino-methyl)phenyl]methanol hydrochloride (34403-46-8)

Guidance literature:

4-cyanobenzaldehyde; With C₂₈H₂₉Cl₂CoNP₂; hydrogen; sodium triethylborohydride; In 1,4-dioxane; at 80 ℃; for 6h; under 37503.8 Torr;

With hydrogenchloride;

DOI:10.1039/c9cy00225a

Reference yield: 89.0%

[4-(azidomethyl)phenyl]methanol (439691-96-0) → [4-(amino-methyl)phenyl]methanol hydrochloride (34403-46-8)

Guidance literature:

[4-(azidomethyl)phenyl]methanol; With triphenylphosphine; at 110 ℃; for 20h; Green chemistry;

With hydrogenchloride; In 1,4-dioxane; diethyl ether; Green chemistry;

DOI:10.1039/c8gc02136h

Reference yield: 81.0%

4-cyanobenzoic acid methyl ester (1129-35-7) → [4-(amino-methyl)phenyl]methanol hydrochloride (34403-46-8)

Guidance literature:

4-cyanobenzoic acid methyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 50 ℃; for 16h; Inert atmosphere;

With water; sodium hydroxide; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;

DOI:10.1021/ja2107564

upstream raw materials:

tert-butyl 4-hydroxymethylbenzylcarbamate

4-cyanobenzaldehyde

4-cyanobenzoic acid methyl ester

[4-(azidomethyl)phenyl]methanol

Downstream raw materials:

N-(4-(hydroxymethyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide

7-(3,5-dimethoxyphenylamino)-5-(4-hydroxymethylbenzylamino)imidazo[1,2-c]pyrimidine-8-carboxamide

C₇₃H₉₁N₅O₁₂

C₃₉H₄₉N₃O₆