(E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid

Base Information

• Chemical Name: (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid
• CAS No.: 197724-51-9
• Molecular Formula: C₃₀H₂₅N₃O₄
• Molecular Weight: 491.546
• Mol file: 197724-51-9.mol

Synonyms:(E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid

Chemical Property of (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid

There total 5 articles about (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine (95753-56-3,324017-21-2) + Nitrosobenzene (586-96-9) → (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid (197724-51-9)

Guidance literature:

With acetic acid; for 24h; Heating;

DOI:10.1002/cmdc.202000280

Reference yield:

4-nitro-3-phenyl-L-alanine (949-99-5) → (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid (197724-51-9)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd/BaSO₄ / H₂O

2: AcOH

3: NaHCO₃ / H₂O; acetone

With hydrogen; sodium hydrogencarbonate; acetic acid; Pd-BaSO₄; In water; acetone;

DOI:10.1246/cl.1998.537

Reference yield:

4-amino-L-phenylalanine (943-80-6) → (E)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phenyldiazenyl)phenyl)propanoic acid (197724-51-9)

Guidance literature:

Multi-step reaction with 2 steps

1: AcOH

2: NaHCO₃ / H₂O; acetone

With sodium hydrogencarbonate; acetic acid; In water; acetone;

DOI:10.1246/cl.1998.537

upstream raw materials:

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine

Nitrosobenzene

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

L-phenylalanine-4'-azobenzene