Technology Process of 5,7-diisopropoxy-3-(phenylthio)isobenzofuran-1(3H)-one
There total 6 articles about 5,7-diisopropoxy-3-(phenylthio)isobenzofuran-1(3H)-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
toluene;
at 20 ℃;
for 72h;
Inert atmosphere;
DOI:10.1039/c3ob41951g
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: caesium carbonate; tetra-(n-butyl)ammonium iodide / acetone; N,N-dimethyl-formamide / Reflux; Inert atmosphere
2.1: trimethylaluminum / toluene; hexane / 20 °C / Inert atmosphere
3.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere
3.2: -78 - 20 °C / Inert atmosphere
4.1: potassium hydroxide / tetrahydrofuran; water / 20 °C
5.1: toluene-4-sulfonic acid / toluene / 72 h / 20 °C / Inert atmosphere
With
N,N,N,N,-tetramethylethylenediamine; trimethylaluminum; tert.-butyl lithium; tetra-(n-butyl)ammonium iodide; caesium carbonate; toluene-4-sulfonic acid; potassium hydroxide;
In
tetrahydrofuran; hexane; water; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1039/c3ob41951g
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuric acid / water / 120 h / Reflux; Inert atmosphere
2.1: caesium carbonate; tetra-(n-butyl)ammonium iodide / acetone; N,N-dimethyl-formamide / Reflux; Inert atmosphere
3.1: trimethylaluminum / toluene; hexane / 20 °C / Inert atmosphere
4.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere
4.2: -78 - 20 °C / Inert atmosphere
5.1: potassium hydroxide / tetrahydrofuran; water / 20 °C
6.1: toluene-4-sulfonic acid / toluene / 72 h / 20 °C / Inert atmosphere
With
N,N,N,N,-tetramethylethylenediamine; sulfuric acid; trimethylaluminum; tert.-butyl lithium; tetra-(n-butyl)ammonium iodide; caesium carbonate; toluene-4-sulfonic acid; potassium hydroxide;
In
tetrahydrofuran; hexane; water; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1039/c3ob41951g
