S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Base Information

Chemical Name:S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate
CAS No.:343969-48-2
Molecular Formula:C₃₀H₄₄O₅S₂
Molecular Weight:548.808
Hs Code.:

Synonyms:S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Suppliers and Price of S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

There total 4 articles about S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1120-73-6
2-methyl-2-cyclopenten-1-one

: 66613-24-9
(phenylsulfanyl)methyl vinyl ketone

: (1E/Z)-1-(tert-butylthio)-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]-1-(trimethylsilyloxy)prop-1-ene

: 343969-48-2
S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Guidance literature:: triphenylmethylium hexachloroantimonate(V); In dichloromethane; at -78 ℃;
DOI:10.1016/S0040-4039(01)00317-3

Reference yield:

: 332950-54-6
S-tert-butyl 3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

: 343969-48-2
S-tert-butyl (2S)-[(1S,2S)-3-oxo-2-(3-oxo-4-phenylthiobutyl)cyclopentyl-]-3-[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]propanethioate

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / LDA

2: 75 percent / TrSbCl₆ / CH₂Cl₂ / -78 °C

With lithium diisopropyl amide; triphenylmethylium hexachloroantimonate(V); In dichloromethane; 2: Mukaiyama-Michael reaction;
DOI:10.1016/S0040-4039(01)00317-3