2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

Base Information

Chemical Name:2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole
CAS No.:159885-79-7
Molecular Formula:C₁₅H₇F₆N₃O₂S
Molecular Weight:407.296
Hs Code.:

Synonyms:2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

Suppliers and Price of 2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

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Technology Process of 2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

There total 6 articles about 2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 159885-60-6
2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

: 159885-79-7
2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

Guidance literature:: With potassium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1021/jm00001a008

Reference yield:

: 159885-58-2
4-carboetoxy-5-(trifluoromethyl)pyrazole-1-thioamide

: 159885-79-7
2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

Guidance literature:: Multi-step reaction with 2 steps

2: NaOH / ethanol

With sodium hydroxide; In ethanol;
DOI:10.1021/jm00007a002

Reference yield:

: 1048670-08-1
2-[1-ethoxy-meth-(Z)-ylidene]-4,4,4-trifluoro-3-oxo-butyric acid ethyl ester

: 159885-79-7
2-<4-carboxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) EtOH, RT, 1 h, 2.) EtOH, refux, 3 h

2: 96 percent / KOH / ethanol / 3 h / Heating

With potassium hydroxide; In ethanol;
DOI:10.1021/jm00001a008