benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate

Base Information

• Chemical Name: benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate
• CAS No.: 1537185-83-3
• Molecular Formula: C₁₆H₂₃NO₂Sn
• Molecular Weight: 380.074
• Mol file: 1537185-83-3.mol

Synonyms:benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate

Chemical Property of benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate

There total 1 articles about benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

hexamethyldistannane (661-69-8) + benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate (286961-24-8) → benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate (1537185-83-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In 1,4-dioxane; for 1.5h; Reflux; Inert atmosphere;

DOI:10.1134/S1070363213120256

Reference yield: 89.0%

(2E,6E)-farnesyl acetate (4128-17-0) + benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate (1537185-83-3) → benzyl 4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-3,6-dihydropyridine-1(2H)-carboxylate (1537185-93-5)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; lithium chloride; In 1-methyl-pyrrolidin-2-one; at 50 - 55 ℃; Inert atmosphere;

DOI:10.1134/S1070428013120269

Reference yield: 80.0%

benzyl 4-trimethylstannyl-3,6-dihydro-2H-pyridine-1-carboxylate (1537185-83-3) + allyl bromide (106-95-6) → benzyl 4-allyl-3,6-dihydro-2H-pyridine-1-carboxylate (1555377-01-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In 1,4-dioxane;

DOI:10.1134/S1070363213120256

upstream raw materials:

hexamethyldistannane

benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate

Downstream raw materials:

benzyl 4-allyl-3,6-dihydro-2H-pyridine-1-carboxylate

benzyl 4-[(E)-but-2-enyl]-3,6-dihydro-2H-pyridine-1-carboxylate

benzyl 4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,6-dihydropyridine-1(2H)-carboxylate

benzyl 4-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-3,6-dihydropyridine-1(2H)-carboxylate