(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Base Information

Chemical Name:(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester
CAS No.:904681-40-9
Molecular Formula:C₁₁H₁₇F₃O₄S
Molecular Weight:302.315
Hs Code.:

Synonyms:(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Suppliers and Price of (R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

There total 5 articles about (R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 904681-39-6
(R)-(+)-3-(2-hydroxy-1,1-dimethylethyl)cyclohexanone

: 358-23-6
trifluoromethylsulfonic anhydride

: 904681-40-9
(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/ja063332y

Reference yield:

: 904681-38-5
(R)-2-methyl-2-(3-oxocyclohexyl)propionic acid methyl ester

: 904681-40-9
(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1.69 g / p-TSA / methanol / 2 h / 23 °C

2: lithium aluminum hydride / tetrahydrofuran / 3 h / 0 - 23 °C

3: 1.22 g / aq. KOH / 12 h / 23 °C

4: 73 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 °C

With 2,6-dimethylpyridine; potassium hydroxide; lithium aluminium tetrahydride; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja063332y

Reference yield:

: 2-((R)-3,3-Dimethoxy-cyclohexyl)-2-methyl-propan-1-ol

: 904681-40-9
(R)-(+)-trifluoromethanesulfonic acid 2-methyl-2-(3-oxocyclohexyl)propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.22 g / aq. KOH / 12 h / 23 °C

2: 73 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 °C

With 2,6-dimethylpyridine; potassium hydroxide; In dichloromethane;
DOI:10.1021/ja063332y