N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide

Base Information

• Chemical Name: N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide
• CAS No.: 330790-85-7
• Molecular Formula: C₂₉H₂₆Cl₂FN₇O₄S
• Molecular Weight: 658.54

Synonyms:N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide

Chemical Property of N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide

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Technology Process of N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide

There total 1 articles about N₁-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

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ethyl 2-[4-amino-3-(4-[(2,3-dichlorophenyl)sulfonyl]amino-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetate (330788-92-6) + (+)-(1S,2R)-ephedrine hydrochloride (24221-86-1) → N1-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-NI-methyl-2-[4-amino-3-(4-{[(2,3-dichlorophenyl)sulfonyl]amino}-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetamide (330790-85-7)

Guidance literature:

In aqueous ammonium acetate; acetonitrile;

upstream raw materials:

ethyl 2-[4-amino-3-(4-[(2,3-dichlorophenyl)sulfonyl]amino-3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]acetate

(+)-(1S,2R)-ephedrine hydrochloride

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