24221-86-1Relevant academic research and scientific papers
Gamma-polymorph of a substituted pyrazoline, its preparation and use as medicaments
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, (2008/12/06)
The present invention relates to the γ-Polymorph of (R)-N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide, methods for its preparation, medicaments comprising this compound as well as their use for the preparation of a medicament for the treatment of humans and animals.
OPTICAL RESOLUTION OF 3-endo-BENZAMIDO-5-NORBORNENE-2-endo-CARBOXYLIC ACID AND ITS APPLICATION AS A NEW RESOLVING AGENT
Saigo, Kazuhiko,Okuda, Yoshiyuki,Wakabayashi, Sumio,Hoshiko, Tomonori,Nohira, Hiroyuki
, p. 857 - 860 (2007/10/02)
3-endo-Benzamido-5-norbornene-2-endo-carboxylic acid was synthesized from 5-norbornene-2-endo 3-endo-dicarboxylic anhydride in one pot and easily resolved into a pair of optically active forms by preferential crystallization of its dibenzylamine salt.The optically active acid was successfully applied to the optical resolution of (+/-)-ephedrine as a new resolving agent.
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