N,N'-1H-Purine-2,6-diybis acetamide

Base Information

• Chemical Name: N,N'-1H-Purine-2,6-diybis acetamide
• CAS No.: 34097-37-5
• Molecular Formula: C9H10 N6 O2
• Molecular Weight: 234.217
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID20552531
• Nikkaji Number: J1.036.795F
• Wikidata: Q82432845
• Mol file: 34097-37-5.mol

Synonyms:N,N'-1H-Purine-2,6-diybis acetamide;34097-37-5;2,6-diacetamidopurine;N,N'-(1H-purine-2,6-diyl)diacetamide;N-(2-ACETAMIDO-7H-PURIN-6-YL)ACETAMIDE;2.6-diacetamidopurine;SCHEMBL750335;SCHEMBL9021288;DTXSID20552531;UITDLMKGFBJWPJ-UHFFFAOYSA-N;MFCD04972513;AKOS015961165;N,N'-(7H-Purine-2,6-diyl)diacetamide;AC-13145;BS-49169;N,N-1H-PURINE-2,6-DIYBISACETAMIDE;F87955

Chemical Property of N,N'-1H-Purine-2,6-diybis acetamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 119.64000
• Density: 1.585g/cm³
• LogP: 1.56870
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 234.08652358
• Heavy Atom Count: 17
• Complexity: 323

Purity/Quality:

99%, ^*data from raw suppliers

N,N'-1H-PURINE-2,6-DIYBIS ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=NC(=NC2=C1NC=N2)NC(=O)C

Technology Process of N,N'-1H-Purine-2,6-diybis acetamide

There total 3 articles about N,N'-1H-Purine-2,6-diybis acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acetic anhydride (108-24-7) + 2,6-diaminopurine (1904-98-9) → 2,6-bisacetamidopurine (34097-37-5)

Guidance literature:

for 3h; Reflux;

DOI:10.1002/ejoc.201800886

Reference yield:

benzoic acid anhydride (93-97-0) + 2,6-diaminopurine (1904-98-9) → N,N'-(7(9)H-purine-2,6-diyl)-bis-acetamide (34097-37-5)

Guidance literature:

DOI:10.1021/ja01148a071

Reference yield:

→ 2,6-bisacetamidopurine (34097-37-5)

Guidance literature:

DOI:10.1002/jhet.5570160129

upstream raw materials:

benzoic acid anhydride

2,6-diaminopurine

acetic anhydride

Downstream raw materials:

6-Amino-9-(2-benzyloxy-1-benzyloxymethyl-ethoxymethyl)-3,9-dihydro-purin-2-one

9-(2-Benzyloxy-1-benzyloxymethyl-ethoxymethyl)-9H-purine-2,6-diamine

9-(2-Benzyloxy-1-benzyloxymethyl-ethoxymethyl)-2-fluoro-9H-purin-6-ylamine

2-(6-Amino-2-fluoro-purin-9-ylmethoxy)-3-benzyloxy-propan-1-ol