2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Base Information

Chemical Name:2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one
CAS No.:240815-52-5
Molecular Formula:C₉H₅ClN₄O
Molecular Weight:220.618
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80573762
Nikkaji Number:J1.528.949J
Wikidata:Q82462582
Mol file:240815-52-5.mol

Synonyms:240815-52-5;2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one;2-CHLOROIMIDAZO[1,5-A]PYRIDO[3,2-E]PYRAZIN-6-OL;12-chloro-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,10,12-pentaen-7-one;SCHEMBL4038168;DTXSID80573762;AB44517;CS-0493080;G67302

Suppliers and Price of 2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one 95+%
1g
$ 608.00

American Custom Chemicals Corporation
2-CHLOROIMIDAZO-[1,5-A]PYRIDO-[3,2-E]PYRAZIN-6-OL 95.00%
5MG
$ 496.13

Alichem
2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one
1g
$ 504.90

Total 4 raw suppliers

Chemical Property of 2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Chemical Property:

Boiling Point:355.6±42.0 °C(Predicted)
PKA:11.58±0.20(Predicted)
PSA：63.31000
Density:1.78±0.1 g/cm3(Predicted)
LogP:1.63650
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:220.0151885
Heavy Atom Count:15
Complexity:287

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC2=C1NC(=O)C3=CN=CN32)Cl

Technology Process of 2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

There total 3 articles about 2-Chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 240815-51-4
3H-imidazole-4-carboxylic acid (2,6-dichloro-pyridin-3-yl)-amide

: 240815-52-5
2-chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl acetamide; Heating;
DOI:10.1016/S0040-4039(01)00698-0

Reference yield:

: 62476-56-6
3-amino-2,6-dichloropyridine

: 240815-52-5
2-chloroimidazo[1,5-a]pyrido[3,2-e]pyrazin-6(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / -10 °C

1.2: tetrahydrofuran / 20 °C

2.1: potassium carbonate / N,N-dimethyl-acetamide / Heating

With sodium hexamethyldisilazane; potassium carbonate; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1021/jm030217e