UDP-N-acetylmuramic acid α-anomer

Base Information

• Chemical Name: UDP-N-acetylmuramic acid α-anomer
• CAS No.: 18867-75-9
• Molecular Formula: C₂₀H₃₁N₃O₁₉P₂
• Molecular Weight: 679.422
• Mol file: 18867-75-9.mol

Synonyms:UDP-N-acetylmuramic acid α-anomer

Chemical Property of UDP-N-acetylmuramic acid α-anomer

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of UDP-N-acetylmuramic acid α-anomer

There total 2 articles about UDP-N-acetylmuramic acid α-anomer which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

triethylammonium muramyl phosphate + uridine 5'-monophosphomorpholidate 4-morpholine-N,N'-dicyclohexyl carboxamidine salt → UDP (58-98-0) + Up2U (26184-65-6) + UDP-N-acetylmuramic acid α-anomer (18867-75-9)

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 15h;

DOI:10.1691/ph.2008.7675

Reference yield: 52.0%

uridine 5'-monophosphate morpholidate (27908-36-7) + (R)-2-((2R,3R,4R,5S,6R)-3-Acetylamino-5-hydroxy-6-hydroxymethyl-2-phosphonooxy-tetrahydro-pyran-4-yloxy)-propionic acid; compound with triethyl-amine → Up2U (26184-65-6) + UDP-N-acetylmuramic acid α-anomer (18867-75-9)

Guidance literature:

With 4 A molecular sieve; In N,N-dimethyl-formamide; at 70 ℃; for 10h;

DOI:10.1016/S0960-894X(99)00638-1

Reference yield:

UDP-N-acetylmuramic acid α-anomer (18867-75-9) → N-{(R)-2-[2-acetylamino-O1-(1,2-dihydroxy-2-uridin-5'-yloxy-diphosphoryl)-2-deoxy-α-D-glucopyranose-3-yloxy]-propionyl}-L-alanine (1941-66-8,40720-21-6,78738-65-5)

Guidance literature:

With L-alanin; Biosynthese mit Hilfe von UDP-N-acetylmuramoyl-alanin-synthetase aus Staphylococcus aureus;

upstream raw materials:

uridine 5'-monophosphate morpholidate

Downstream raw materials:

N-{(R)-2-[2-acetylamino-O¹-(1,2-dihydroxy-2-uridin-5'-yloxy-diphosphoryl)-2-deoxy-α-D-glucopyranose-3-yloxy]-propionyl}-L-alanine