3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol

Base Information

Chemical Name:3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol
CAS No.:239074-65-8
Molecular Formula:C9H7 Cl2 F3 O
Molecular Weight:259.055
Hs Code.:2906299090
DSSTox Substance ID:DTXSID80433433
Nikkaji Number:J1.583.504D
Mol file:239074-65-8.mol

Synonyms:3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol;239074-65-8;DTXSID80433433;AAJFTUIEAYJREB-UHFFFAOYSA-N;MFCD08458158;AKOS025310314;1,1,1-Trifluoro-2-phenyl-3,3-dichloro-2-propanol

Suppliers and Price of 3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol 97%
5 g
$ 350.00

SynQuest Laboratories
3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol 97%
1 g
$ 110.00

American Custom Chemicals Corporation
3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL 95.00%
5G
$ 1045.28

American Custom Chemicals Corporation
3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL 95.00%
1G
$ 675.68

Total 9 raw suppliers

Chemical Property of 3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.497
Boiling Point:291.098°C at 760 mmHg
Flash Point:129.851°C
PSA：20.23000
Density:1.466g/cm³
LogP:3.24020
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:257.9826047
Heavy Atom Count:15
Complexity:214

Purity/Quality:

97% ^*data from raw suppliers

3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(Cl)Cl)(C(F)(F)F)O

Technology Process of 3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol

There total 2 articles about 3,3-Dichloro-1,1,1-trifluoro-2-phenylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 126266-75-9
3,3-dichloro-1,1,1-trifluoroacetone

: phenylmagnesium bromide

: 239074-65-8
1,1-dichloro-2-trifluoromethyl-4-phenylbutan-2-ol

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/j.tet.2003.09.098

Reference yield:

: 126266-75-9
3,3-dichloro-1,1,1-trifluoroacetone

: 239074-65-8
1,1-dichloro-2-trifluoromethyl-4-phenylbutan-2-ol

Guidance literature:: DOI:10.1002/anie.200353032

Reference yield: 69.0%

: 75-16-1
methylmagnesium bromide

: 917-54-4
methyllithium

: 239074-65-8
1,1-dichloro-2-trifluoromethyl-4-phenylbutan-2-ol

: 109662-31-9
1,1,1-trifluoro-3-methyl-2-phenylbut-2-en

Guidance literature:: methylmagnesium bromide; 1,1-dichloro-2-trifluoromethyl-4-phenylbutan-2-ol; In tetrahydrofuran; at -78 ℃; for 1h;

methyllithium; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃;
DOI:10.1016/j.tet.2003.09.098