1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea

Base Information

• Chemical Name: 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea
• CAS No.: 173908-91-3
• Molecular Formula: C₂₂H₁₈N₄O₃
• Molecular Weight: 386.41

Synonyms:1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea

Chemical Property of 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea

There total 7 articles about 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

phenyl isocyanate (103-71-9) + 3-amino-1-phenyl-1,5-dihydrobenzo<1,4>diazepine-2,4-dione (153930-38-2) → 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea (173908-91-3)

Guidance literature:

In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jm950626d

Reference yield:

N-(4-methoxybenzyl)-N-phenylbenzene-1,2-diamine (161455-85-2) → 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea (173908-91-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 83 percent / tetrahydrofuran / 16 h / Ambient temperature

2: 98 percent / Zn / acetic acid / 3 h / Ambient temperature

3: 87 percent / (NH₄)2Ce(NO₃)6 / acetonitrile; H₂O / Ambient temperature

4: 72 percent / CH₂Cl₂ / 2 h / Ambient temperature

With ammonium cerium(IV) nitrate; zinc; In tetrahydrofuran; dichloromethane; water; acetic acid; acetonitrile;

DOI:10.1021/jm950626d

Reference yield:

4-methoxy-N-(2-(phenylamino)phenyl)benzamide (161455-84-1) → 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea (173908-91-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 100 percent / LiAlH₄ / tetrahydrofuran / 1.5 h / Heating

2: 83 percent / tetrahydrofuran / 16 h / Ambient temperature

3: 98 percent / Zn / acetic acid / 3 h / Ambient temperature

4: 87 percent / (NH₄)2Ce(NO₃)6 / acetonitrile; H₂O / Ambient temperature

5: 72 percent / CH₂Cl₂ / 2 h / Ambient temperature

With lithium aluminium tetrahydride; ammonium cerium(IV) nitrate; zinc; In tetrahydrofuran; dichloromethane; water; acetic acid; acetonitrile;

DOI:10.1021/jm950626d

upstream raw materials:

phenyl isocyanate

3-amino-1-phenyl-1,5-dihydrobenzo<1,4>diazepine-2,4-dione

N-(4-methoxybenzyl)-N-phenylbenzene-1,2-diamine

4-methoxy-N-(2-(phenylamino)phenyl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 173908-91-3 1-(2,4-dioxo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo<1,4>diazepin-3-yl)-3-phenylurea

Send

Send

Metric Ton KG G Pound L ML

Send

Send