diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate

Base Information

• Chemical Name: diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate
• CAS No.: 1235983-71-7
• Molecular Formula: C₁₇H₂₁N₃O₆
• Molecular Weight: 363.37
• Mol file: 1235983-71-7.mol

Synonyms:diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate

Chemical Property of diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate

There total 1 articles about diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

di-isopropyl azodicarboxylate (2446-83-5) + 3-(4-nitrophenyl)prop-2-yn-1-ol (61266-32-8) → diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate (1235983-71-7)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol101365x

Reference yield: 23.0%

diisopropyl 1-(3-(4-nitrophenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate (1235983-71-7) → diisopropyl 2,5-dihydro-4-iodo-3-(4-nitrophenyl)-1H-pyrazole-1,2-dicarboxylate (1235983-50-2)

Guidance literature:

With bis(2,4,6-collidine)-iodonium(I) hexafluorophosphate; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol101365x

upstream raw materials:

di-isopropyl azodicarboxylate

3-(4-nitrophenyl)prop-2-yn-1-ol

Downstream raw materials:

diisopropyl 2,5-dihydro-4-iodo-3-(4-nitrophenyl)-1H-pyrazole-1,2-dicarboxylate