11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

Base Information

Chemical Name:11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
CAS No.:1977-07-7
Molecular Formula:C₁₈H₂₀N₄
Molecular Weight:292.384
Hs Code.:
DSSTox Substance ID:DTXSID80173463
Nikkaji Number:J42.193F
ChEMBL ID:CHEMBL73538
Mol file:1977-07-7.mol

Synonyms:106-094;11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

Suppliers and Price of 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 97%
100mg
$ 455.00

Crysdot
11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 97%
50mg
$ 289.00

ChemScene
Deschloroclozapine 99.79%
10mg
$ 100.00

ChemScene
Deschloroclozapine 99.79%
100mg
$ 550.00

ChemScene
Deschloroclozapine 99.79%
50mg
$ 350.00

American Custom Chemicals Corporation
11-(4-METHYL-1-PIPERAZINYL)-5H-DIBENZO(B,E)(1,4)DIAZEPINE 95.00%
5MG
$ 496.91

Alichem
11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
100mg
$ 780.00

Alichem
11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
50mg
$ 530.40

Alichem
11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
25mg
$ 374.50

Total 14 raw suppliers

Chemical Property of 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

Chemical Property:

Vapor Pressure:1.48E-08mmHg at 25°C
Boiling Point:457.5°Cat760mmHg
PKA:7.82±0.20(Predicted)
Flash Point:230.5°C
PSA：30.87000
Density:1.22g/cm³
LogP:2.51870
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:292.16879665
Heavy Atom Count:22
Complexity:413

Purity/Quality:

97% ^*data from raw suppliers

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCN(CC1)C2=NC3=CC=CC=C3NC4=CC=CC=C42

Technology Process of 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

There total 8 articles about 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 109-01-3
1-methyl-piperazine

: 5814-41-5
5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one

: 1977-07-7
11-(4-methylpiperazino)-5H-dibenzo<1,4>diazepine

Guidance literature:: 5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one; With trichlorophosphate; In N,N-dimethyl-aniline; at 130 ℃; for 12h; Inert atmosphere;

1-methyl-piperazine; In N,N-dimethyl-aniline; for 12h;

Reference yield: 72.0%

: N-{2-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-N-(2-nitrophenyl)amine

: 1977-07-7
11-(4-methylpiperazino)-5H-dibenzo<1,4>diazepine

Guidance literature:: With tributylphosphine; at 150 ℃; for 48h;
DOI:10.1021/acs.joc.8b02682

Reference yield:

: 1829-28-3
ethyl 2-iodobenzoate

: 1977-07-7
11-(4-methylpiperazino)-5H-dibenzo<1,4>diazepine

Guidance literature:: Multi-step reaction with 2 steps

1.1: copper(l) iodide / ethylene glycol / 1 h / 180 °C / Microwave irradiation; Inert atmosphere

2.1: trichlorophosphate / N,N-dimethyl-aniline / 12 h / 130 °C / Inert atmosphere

2.2: 12 h

With copper(l) iodide; trichlorophosphate; In ethylene glycol; N,N-dimethyl-aniline;