(S)-(+)-S-METHYL-S-PHENYLSULFOXIMINE

Base Information

• Chemical Name: (S)-(+)-S-METHYL-S-PHENYLSULFOXIMINE
• CAS No.: 33903-50-3
• Molecular Formula: C₇H₉NOS
• Molecular Weight: 155.221
• Hs Code.: 2925290090
• Mol file: 33903-50-3.mol

Synonyms:Sulfoximine,S-methyl-S-phenyl-, (S)-; Sulfoximine, S-methyl-S-phenyl-, (S)-(+)- (8CI);(S)-(+)-Methyl phenyl sulfoximine; (S)-S-Methyl-S-phenylsulfoximine

Chemical Property of (S)-(+)-S-METHYL-S-PHENYLSULFOXIMINE

Chemical Property:

• Melting Point: 30-32°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 49.30000
• Density: g/cm³
• LogP: 2.68750
• Sensitive.: Hygroscopic

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-(+)-MethylPhenylSulfoximine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: A new ligand for assymmetric catalysis A new ligand for assymmetric catalysis.

Technology Process of (S)-(+)-S-METHYL-S-PHENYLSULFOXIMINE

There total 42 articles about (S)-(+)-S-METHYL-S-PHENYLSULFOXIMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C10H16O4S*C7H9NOS (7044-59-9) → (S)-S-methyl-S-phenylsulfoximine (4381-25-3,33903-50-3,60933-65-5,81162-81-4)

Guidance literature:

With sodium hydroxide; In dichloromethane; water;

DOI:10.1002/anie.202016968

Reference yield: 93.0%

(S)-methylphenylsulfoxide (1193-82-4,4850-71-9,18453-46-8,20696-08-6) → (S)-S-methyl-S-phenylsulfoximine (4381-25-3,33903-50-3,60933-65-5,81162-81-4)

Guidance literature:

With 1,10-Phenanthroline; O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; iron(II) sulfate; In acetonitrile; at 30 ℃; for 48h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201710498

Reference yield: 83.0%

(S)-N-(4-nitro-benzenesulfonyl)-S-methyl-S-phenylsulfoximine → (S)-S-methyl-S-phenylsulfoximine (4381-25-3,33903-50-3,60933-65-5,81162-81-4)

Guidance literature:

With caesium carbonate; thiophenol; In acetonitrile; at 20 ℃;

DOI:10.1021/ol060640s

upstream raw materials:

(S)-methylphenylsulfoxide

S-methyl-S-phenylsulfoximine

racemic methyl phenyl sulfoxide

(R)-methyl phenyl sulfoxide

Downstream raw materials:

(+)-(S_S)-S-methyl-S-phenyl-N-(trimethylsilyl)sulfoximine

N,S-dimethyl-S-phenylsulfoximine

(+)-(S)-N-(3-Hydroxypropyl)-S-methyl-S-phenylsulfoximine

(S)-N-[2-nitro-4-trifluoromethylphenyl]-S-methyl-S-phenylsulfoximine