tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Base Information

Chemical Name:tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate
CAS No.:168264-11-7
Molecular Formula:C₂₅H₃₄N₄O₇
Molecular Weight:502.568
Hs Code.:

tert-butyl 4-(N<sub>4</sub>-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Synonyms:tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Suppliers and Price of tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

There total 2 articles about tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 149411-91-6
N-benzyloxycarbonyl cytosine

: 163210-89-7
tert-butyl (S)-2-[(tert-butoxycarbonyl)amino]-4-bromobutanoate

: 168264-11-7
tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; caesium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 16h;
DOI:10.1021/jacs.0c08964

Reference yield:

: 24277-39-2
N-tert-butoxycarbonyl glutamic acid tert-butyl ester

: 168264-11-7
tert-butyl 4-(N₄-benzyloxycarbonylcytosin-1-yl)-2S-butoxycarbonylaminobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / CBrCl₃; 2-mercaptopyridine N-oxide; DCC / DMAP / tetrahydrofuran / 4 h / 0 - 20 °C / Irradiation

2: 50 percent / K₂CO₃; Cs₂CO₃; TBAI / dimethylformamide / 50 °C

With Bromotrichloromethane; tetra-(n-butyl)ammonium iodide; potassium carbonate; caesium carbonate; dicyclohexyl-carbodiimide; 2-mercaptopyridine N-oxide; dmap; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(00)00324-2