4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture)

Base Information

• Chemical Name: 4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture)
• CAS No.: 33893-85-5
• Molecular Formula: C7H14 O2
• Molecular Weight: 130.187
• Hs Code.: 2906199090
• Mol file: 33893-85-5.mol

Synonyms:1-(Hydroxymethyl)cyclohexan-4-ol;4-(Hydroxymethyl)cyclohexanol; 4-Hydroxycyclohexanemethanol; 4-Methanolcyclohexanol

Chemical Property of 4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture)

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Melting Point: 28 °C
• Refractive Index: 1.493
• Boiling Point: 122 °C / 1mmHg
• PKA: 15.05±0.10(Predicted)
• Flash Point: 127.191°C
• PSA: 80.92000
• Density: 1.067g/cm³
• LogP: 1.05960
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol

Purity/Quality:

97% ^*data from raw suppliers

4-(Hydroxymethyl)cyclohexan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture)

There total 6 articles about 4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-hydroxycyclohexyl carboxylic acid ethyl ester (3618-04-0,75877-66-6,17159-80-7) → 4-(hydroxymethyl)cyclohexan-1-ol (33893-85-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;

Reference yield:

piperonal (120-57-0,30024-74-9) → 4-(hydroxymethyl)cyclohexan-1-ol (33893-85-5) + trans-4-methylcyclohexan-1-ol (7731-29-5)

Guidance literature:

With ethanol; nickel; at 35 - 135 ℃; Hydrogenation;

Reference yield:

piperonal (120-57-0,30024-74-9) + ethanol (64-17-5) → 4-(hydroxymethyl)cyclohexan-1-ol (33893-85-5) + trans-4-methylcyclohexan-1-ol (7731-29-5)

Guidance literature:

at 135 ℃; unter Druck_.Hydrogenation;

upstream raw materials:

piperonal

ethanol

4-hydroxycyclohexyl carboxylic acid ethyl ester

4-carbomethoxycyclohexanone

Downstream raw materials:

pyrrolidine-1-carboxylic acid 4-phenethylcarbamoyloxy-cyclohexylmethyl ester