Technology Process of 1H-Azepine-1-carboxylic acid, 3-aMinohexahydro-, phenylMethyl ester
There total 2 articles about 1H-Azepine-1-carboxylic acid, 3-aMinohexahydro-, phenylMethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
[4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; 2,4,6-Triisopropylthiophenol; ammonia;
In
methanol; toluene;
at 20 ℃;
for 16h;
regioselective reaction;
Inert atmosphere;
Irradiation;
DOI:10.1002/chem.202003562
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium triethylborohydride / toluene; tetrahydrofuran / 0.75 h / -78 °C
1.2: 16 h / -78 - 20 °C
2.1: 2,4,6-Triisopropylthiophenol; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; ammonia / toluene; methanol / 16 h / 20 °C / Inert atmosphere; Irradiation
With
[4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; 2,4,6-Triisopropylthiophenol; ammonia; lithium triethylborohydride;
In
tetrahydrofuran; methanol; toluene;
DOI:10.1002/chem.202003562
