3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone

Base Information

• Chemical Name: 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone
• CAS No.: 227002-84-8
• Molecular Formula: C₁₄H₁₈N₄O₄
• Molecular Weight: 306.321
• Mol file: 227002-84-8.mol

Synonyms:3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone

Chemical Property of 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone

There total 3 articles about 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

L-threo-2,3-hexodiulosono-1,4-lactone-2-(p-tolylhydrazone) (65827-00-1) + methylhydrazine (60-34-4) → 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone (227002-84-8)

Guidance literature:

In ethanol; for 10h; Heating;

DOI:10.1039/a807584k

Reference yield: 40.0%

L-threo-2,3-hexodiulosono-1,4-lactone-2-p-tolylhydrazone-3-methyl-hydrazone (227002-81-5) → 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone (227002-84-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

DOI:10.1039/a807584k

Reference yield:

L-threo-2,3-hexodiulosono-1,4-lactone-2-(p-tolylhydrazone) (65827-00-1) → 3-(L-threo-glycerol-1-yl)-1-methyl-4,5-pyrazolindione 4-p-tolylhydrazone (227002-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / AcOH / ethanol / 2 h / Heating

2: 40 percent / hydrazine hydrate / ethanol / 1 h / Heating

With hydrazine hydrate; acetic acid; In ethanol; 1: Condensation / 2: Rearrangement;

DOI:10.1039/a807584k

upstream raw materials:

L-threo-2,3-hexodiulosono-1,4-lactone-2-(p-tolylhydrazone)

methylhydrazine

L-threo-2,3-hexodiulosono-1,4-lactone-2-p-tolylhydrazone-3-methyl-hydrazone