Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

Base Information

Chemical Name:Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester
CAS No.:113497-80-6
Molecular Formula:C₁₈H₂₀ClNO₃
Molecular Weight:333.815
Hs Code.:

Synonyms:Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

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Chemical Property of Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

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Technology Process of Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

There total 3 articles about Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7633-32-1
tert-butyl glyoxylate

: 113479-88-2
4-phenylpropargylazetidin-2-one

: 113497-80-6
Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

Guidance literature:: DOI:10.1016/S0040-4039(00)96235-X

Reference yield:

: 591-50-4
iodobenzene

: 113497-80-6
Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / CuI, Pd(Ph₃P)4 / triethylamine

copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In triethylamine;
DOI:10.1016/S0040-4039(00)96235-X

Reference yield:

: 81355-47-7
4-propargyl-2-azetidinone

: 113497-80-6
Chloro-[2-oxo-4-(3-phenyl-prop-2-ynyl)-azetidin-1-yl]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / CuI, Pd(Ph₃P)4 / triethylamine

copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In triethylamine;
DOI:10.1016/S0040-4039(00)96235-X